Project

Connexin and pannexin channels: regulation, function and applications

Code
3WO00510
Duration
01 January 2010 → 31 December 2016
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Other biological sciences
  • Medical and health sciences
    • Physiology
    • Physiology
    • Physiology
Keywords
pannexin inhibitors hemichannels connexins regulation
 
Project description

Research questions: (i) What is the molecular regulation of hemichannels as compared to gap junction channels ? (ii) How can we influence hemichannels without affecting gap junctions ? (iii) What is the role of gap junctions and hemichannels in cell death ? (iv) What is the in vivo role and function of hemichannels and how can we modulate their activity ?