In summary, the purpose of this chair (on the basis of a series of lectures at the Flemish Universities) 1) disseminating scientific knowledge about pain in children with pain is sketched from a biopsychosocial framework; 2) demonstrate the importance of pain research in the context of cancer (pediatric context) with particular attention will be paid to the importance of social context (eg, role of parents, doctors, nurses).; 3) a discussion of recent research regarding this topic and 4) a discussion of future research plans in which a) the role of emotion regulation in caretakers at the sight of pain in children (eg in the context of childhood) and their influence will systematically helping behavior be investigated and b) will be studied systematically what is the impact of childhood cancer on all family members (mothers and fathers and siblings) including family functioning and torque performance and the factors that moderate this effect (protective and risk factors). It is expected that this chair not only disseminating knowledge entails, but both clinical and academic field encourages innovative psychosocial research in the context of childhood with current and future empirical evidence will provide important tools for translation into clinical psychosocial interventions.