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Project

Endosomal Micro-Autophagy as a New Cell Death Checkpoint in the TNF Pathway

Information

Project Team

Organisations

Outputs and Outcomes

Publications

ATG9A-mediated autophagy prevents inflammatory skin disease by limiting TNFR1-driven STING activation and ZBP1-dependent cell death

Dario PriemJon HuygheBarbara GilbertSimon VerdonckTom DelangheBruno VerstraetenEsther HostePeter VandenabeeleJonathan MaelfaitGeert van LooMathieu Bertrand et al.

A1 Journal Article in IMMUNITY

2025

TAB2 controls a TAK1-independent cell death checkpoint at the level of TNFR1 complex II in the TNF pathway

Tom DelangheMike VadiAnnelore HaemsLisa WijnsInge BruggemanJon HuygheDario PriemPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2025

Primidone : a clinically promising candidate for the treatment of psoriasis

Theresa RiebelingBenedikt KolbrinkRebecca PhilippsenEileen DahlkeTom DelangheFranziska TheiligAgatha SchwarzRoland SchmittMathieu BertrandUlrich KunzendorfStefan Krautwald et al.

A1 Journal Article in CELL DEATH DISCOVERY

2025