Project

An integrated metabolomics approach to unravel the pathophysiology of early feline chronic kidney disease.

Code

01D07220

Duration

01 November 2020 → 31 October 2024

Funding

Regional and community funding: Special Research Fund

Promotor

Sylvie Daminet

Fellow

Laurens Van Mulders

Research disciplines

Medical and health sciences
- Medical metabolomics
- Medical proteomics
Agricultural and food sciences
- Veterinary internal medicine and pathophysiology
- Veterinary physiology, pathophysiology and biochemistry
- Zoological medicine

Keywords

Pathophysiology Feline chronic kidney disease (CKD) Integrated metabolomics

Project description

This proposal exploits the analytical power of integrated metabolomics, in silico analysis of multiparametric datasets, and carefully curated prospective clinical cohorts to: (i) better understand CKD pathogenesis in all felids; and (ii) discover new therapeutic targets. These data will pave the way for new early interventions to treat renal failure and provide insights into aetiological factors.