Project

Identification of RIPK4-dependent signalling pathways and the role of RIPK4 in skin homeostasis and disease

Duration
01 October 2013 → 30 September 2017
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Dermatology
    • Morphological sciences
    • Oncology
    • Dermatology
    • Morphological sciences
    • Oncology
    • Dermatology
    • Morphological sciences
    • Oncology
Keywords
skin pathologies skin homeostasis cell signalling keratinocytes epidermis
 
Project description

The skin forms a protective barrier to divers environmental stimuli. Proper keratinocyte differentiation and migration is essential to form a functional epidermis and to prevent skin pathologies. Since we showed that the RIPK4 kinase plays a crucial role in the later processes we will investigate the role of RIPK4 in skin homeostasis, inflammation and cancer.