Project

Naive human embryonic stem cells: the new contender?

Code
01D08114
Duration
01 October 2014 → 12 January 2019
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Genetics
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Nursing
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
Keywords
embryo pluripotency
 
Project description

Recent breakthroughs have described the production of human embryonic stem cells which resemble more the mouse counterparts. These stem cells possess a naive state of pluripotency, in contrast to 'primed' stem cells which show already some differentiation. Different culture protocols enable the derivation of naive human embryonic stem cells, but the question remains which protocol gives rise to the similar naive pluripotency state as in mice.