Code
3F022512
Looptijd
01-10-2012 → 30-09-2016
Financiering
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Onderzoeksdisciplines
-
Medical and health sciences
- Inflammation
Trefwoorden
subsets
monocyten
dendritische cellen
differentiatie
transcriptiefactoren
Projectomschrijving
Interferon regulatory factor (IRF) 4 and IRF8 are two major transcription factors (TFs) implicated in dendritic cell (DC) differentiation. In this project, we will further elucidate the role of IRF4 and IRF8 in the development and biological function of the distinct DC subsets and unravel the complex regulatory networks controlled by these major TFs during DC development and activation.