Code
3F022512
Duration
01 October 2012 → 30 September 2016
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Inflammation
Keywords
development
monocytes
subsets
Transcription factors
dendritic cells
Project description
Interferon regulatory factor (IRF) 4 and IRF8 are two major transcription factors (TFs) implicated in dendritic cell (DC) differentiation. In this project, we will further elucidate the role of IRF4 and IRF8 in the development and biological function of the distinct DC subsets and unravel the complex regulatory networks controlled by these major TFs during DC development and activation.