Project

High throughput analysis of Taenia excretory/secretory products for improved understanding of host-parasite interactions and optimization of immunodiagnostic tools in Taenia solium cysticercosis

Code
3G019210
Duration
01 January 2010 → 31 December 2015
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Medical biochemistry and metabolism
    • Microbiology
    • Tropical medicine
    • Immunology
    • Medical biochemistry and metabolism
    • Microbiology
    • Tropical medicine
    • Immunology
    • Medical biochemistry and metabolism
    • Microbiology
    • Tropical medicine
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
Taenia solium immunodiagnosis host-parasite interaction
 
Project description

Taenia solium cysticercosis is the mot important cause of acquired epilepsy in developing countries. T. solium produces excretory/secretory products (ESP) at the interface between parasite and host. The biological functions of ESP are poorly understood. We propose a mass spectrometic analysis of ESP to better understand their role in host-parasite interactions and to refine existing immunodiagnostic techniques.