Research Explorer

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Project

Generation, characterization and use of immortalized Paneth cells, to elucidate and mimic the therapeutic mechanism of Zinc against infections.

Outputs and Outcomes

Publications

Identification and characterization of multiple Paneth cell types in the mouse small intestine

Steven TimmermansCharlotte WallaeysNatalia Garcia GonzalezLotte PollarisYvan SaeysClaude Libert

A1 Journal Article in CELLS

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Charlotte WallaeysNatalia Garcia GonzalezSteven TimmermansJolien VandewalleTineke VanderhaeghenSomara De BeulHester DufoorMelanie EggermontElise MoensVictor BosteelsRiet De RyckeFabien Henri TheryFrancis ImpensSerge VerbanckStefan LienenklausSophie JanssensRichard S. BlumbergTakao IwawakiClaude Libert et al.

A1 Journal Article in CELL HOST & MICROBE

Exploring Paneth cells : uncovering their homeostatic diversity and role in TNF-induced SIRS

Charlotte WallaeysClaude Libert

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Tineke VanderhaeghenSteven TimmermansMelanie EggermontDeepika WattsJolien VandewalleCharlotte WallaeysLouise NuyttensJoyca De TemmermanTino HochepiedSylviane DewaeleJoke Vanden BergheNiek SandersBen WielockxRudi BeyaertClaude Libert et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY