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Project

Structural basis of regulation of pro-inflammatory IL-17RA by TAOK1 and Act1

Information

Project Team

Organisations

Outputs and Outcomes

Publications

The pros and confs of IL-18 activation

Danielle ClancyJulie AndriesSavvas Savvides

Editorial material

2024

The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement

Maximilian BrinkhausErwin PannecouckeElvera J. van der KooiArthur E. H. BentlageNinotska I. L. DerksenJulie AndriesBianca BalbinoMagdalena SipsPeter UlrichtsPeter VerheesenHans de HaardTheo RispensSavvas SavvidesGestur Vidarsson et al.

A1 Journal Article in NATURE COMMUNICATIONS

2022

Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity

Sammy DetryJulie AndriesYehudi BlochCem GabayDanielle ClancySavvas Savvides

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2022