The ability of cells to divide asymmetrically to produce two different cell types provides the cellular diversity found in every multicellular organism Asymmetric localization of intrinsic cell fate determinants and position within specific environments are examples of mechanisms used to specify cell polarity and direct asymmetric divisions In plants, structures, called stomata, that reside in the epidermis of leaf and stem tissues and allow gas exchange, originate from sequential rounds of asymmetric cell divisions The BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE (BASL) protein functions as an intrinsic factor to mark cell polarity prior to asymmetric divisions in stomatal lineages BASL works in part through a second protein, POLAR Previously, we identified POLAR as a scaffolding protein for a subset of brassinosteroid-regulated GSK3-like/Arabidopsis Shaggy kinases (ASKs) in stomatal lineages POLAR was found to possess four paralogs in the Arabidopsis genome, of which the expression patterns of at least three correlate with the first asymmetric zygotic division Our goal is to characterize the function of the POLAR-like family and to discover whether POLAR-like proteins control asymmetric cell divisions in other cell types Additionally, we aim to detect novel components of the polarization pathway(s) associated with POLAR-like proteins preceding the asymmetric cell divisions and to assess the possible connection with the ASKs