Project

Radiation-induced leukemia: response of CD34+ hematopoietic cells to clinical therapy beams

Code
01N02217
Duration
01 January 2017 → 31 October 2021
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Natural sciences
    • Medicinal and biomolecular chemistry
    • Genetics
    • Molecular and cell biology
    • Plant biology
    • Systems biology
  • Medical and health sciences
    • Biophysics
    • Medical imaging and therapy
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
    • Biophysics
    • Medical imaging and therapy
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
    • Biophysics
    • Medical imaging and therapy
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
Keywords
radiation-induced leukemia radiation qualities stem cells
 
Project description

Leukemia is the most important malignancy after radiation exposure during childhood. The high risk of developing leukemia is related to the high sensitivity of the bone marrow, which harbors hematopoietic stem and progenitor cells (HSPCs). This project aims to elucidate the response of HSPCs (CD34+) to clinical therapy beams of different radiation qualities.