Research Explorer

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Project

Study of the molecular pathways through which linear (de)ubiquitination governs skin inflammation and aberrant epidermal stem cell activation

Outputs and Outcomes

Publications

A20 : a jack of all trades

Pieter HertensGeert van Loo

A1 Journal Article in TRENDS IN CELL BIOLOGY

Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease

Sahana SrinivasanDaliya KanchevaSofie De RenTakashi SaitoMaude JansFleur BooneCharysse VandendriesscheIne PaesmansHerve MaurinRoosmarijn VandenbrouckeEsther HosteSofie VoetIsabelle ScheyltjensBenjamin PavieSaskia LippensMarius SchwabenlandMarco PrinzTakaomi SaidoAstrid BottelbergsKiavash MovahediMohamed LamkanfiGeert van Loo et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion

Maria Giulia DoglioLien VerboomEmily Ruilova SosorangaUlrika FrisingTomoko AsaokaYannick GansemansFilip Van NieuwerburghGeert van LooAndy Wullaert

A1 Journal Article in SCIENCE IMMUNOLOGY

Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice

Karel Van DammePieter HertensArne MartensElisabeth GilisDario PriemInge BruggemanAmelie FossoulJozefien DeclercqHelena Catharine AegerterAndy WullaertTino HochepiedEsther HosteLieselotte Vande WalleMohamed LamkanfiSavvas SavvidesDirk ElewautBart LambrechtGeert van Loo et al.

A1 Journal Article in SCIENTIFIC REPORTS

OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection

Lien VerboomChristopher AndersonMaude JansIoanna PettaGillian BlanckeArne MartensMozes SzeTino HochepiedKodi RavichandranLars VereeckeGeert van Loo et al.

A1 Journal Article in CELL DEATH & DISEASE

Death by TNF : a road to inflammation

Geert van LooMathieu Bertrand

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

A20 controls RANK-dependent osteoclast formation and bone physiology

Arne MartensPieter HertensDario PriemVagelis RinotasTheodore MeletakosMeropi GennadiLisette Van HoveEls LouagieJulie CoudenysAmélie De MuynckDjoere GaublommeMozes SzeJolanda van HengelLeen CatrysseEsther HosteJeffrey D. ZajacRachel A. DaveyLuc Van HoorebekeTino HochepiedMathieu BertrandMarietta ArmakaDirk ElewautGeert van Loo et al.

A1 Journal Article in EMBO REPORTS