Research Explorer

Project

Screening for conjugated fatty acids with milk fat depressing properties through a combination of production, detailed identification and in vitro and in vivo reponse essays
Code
01J08511
Duration
01 July 2011 → 31 August 2016
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
    • Biochemistry and metabolism
    • General biology
    • Systems biology
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
  • Agricultural and food sciences
    • Agricultural animal production
    • Veterinary medicine
Keywords
milk fat conjugated fatty acids dairy cow
 
Project description
 

Low-fat milk syndrome is a challenging biological problem involving the interrelationship between digestive processes and tissue metabolism in several candidate inhibitors will be produced through a combination of isomerisation, hydrogenation or conjugation and subsequently evaluated in vitro using 3T3-L1 cells. Promising inhibitors will be tested in vivo using the dairy cow as a model.