Project

Screening for conjugated fatty acids with milk fat depressing properties through a combination of production, detailed identification and in vitro and in vivo reponse essays

Code

01J08511

Duration

01 July 2011 → 31 August 2016

Funding

Regional and community funding: Special Research Fund

Promotor

Veerle Fievez

Research disciplines

Natural sciences
- Animal biology
- Biochemistry and metabolism
- General biology
- Systems biology
Medical and health sciences
- Medical biochemistry and metabolism
- Medical biochemistry and metabolism
- Medical biochemistry and metabolism
Agricultural and food sciences
- Agricultural animal production
- Veterinary medicine

Keywords

milk fat conjugated fatty acids dairy cow

Project description

Low-fat milk syndrome is a challenging biological problem involving the interrelationship between digestive processes and tissue metabolism in several candidate inhibitors will be produced through a combination of isomerisation, hydrogenation or conjugation and subsequently evaluated in vitro using 3T3-L1 cells. Promising inhibitors will be tested in vivo using the dairy cow as a model.