Research Explorer

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Project

Developing a broadly protecting vaccine against polymicrobial sepsis.

Outputs & Impact

Publications & research data ( 9 )

A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS

Louise NuyttensMarah HeyerickMaxime RoesElise MoensCéline Van DenderCharlotte WallaeysTino HochepiedSteven TimmermansJolien VandewalleClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis

Céline Van DenderSteven TimmermansMaxime RoesMadeleine HellemansElise MoensLouise NuyttensMaarten ClaesBart RomanKarolien De BosscherJolien Vandewalle et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis

Louise NuyttensMarah HeyerickGeike HeremansElise MoensMaxime RoesCéline Van DenderLiesbet De BusJohan DecruyenaereJan De WaeleJolien Vandewalle et al.

A1 Journal Article in CELL REPORTS

Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

Natalia Garcia GonzalezCharlotte WallaeysWendy ToussaintTino HochepiedSylviane DewaeleSomara De BeulRobin Van LokeJolien VandewalleSteven TimmermansRichard S. Blumberg et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Modulation of glucocorticoid receptor function under iron overload

Wanting ZhuTineke VanderhaeghenSteven TimmermansJolien VandewalleMelanie EggermontNicolette J. D. VerhoogClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells

Steven TimmermansCharlotte WallaeysSomara De BeulNatalia Garcia GonzalezClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Tineke VanderhaeghenSteven TimmermansMelanie EggermontDeepika WattsJolien VandewalleCharlotte WallaeysLouise NuyttensJoyca De TemmermanTino HochepiedSylviane Dewaele et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Sepsis : a failing starvation response

Jolien VandewalleClaude Libert

A1 Journal Article in TRENDS IN ENDOCRINOLOGY AND METABOLISM

Dimerization of the glucocorticoid receptor and its importance in (patho)physiology : a primer

Steven TimmermansJolien VandewalleClaude Libert

A1 Journal Article in CELLS

Activities ( 0 )

Results

Impact narratives ( 1 )

Medicine: sepsis

Area(s): Health

Patents ( 0 )