Project

Study of determinants in the immune escape of melanoma and identification of possible strategies to reverse this escape.

Duration
01 October 2010 → 30 September 2012
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Dermatology
    • Immunology
    • Morphological sciences
    • Oncology
    • Dermatology
    • Immunology
    • Morphological sciences
    • Oncology
    • Dermatology
    • Immunology
    • Morphological sciences
    • Oncology
Keywords
immunology dermatology melanoma
 
Project description

Melanoma is a very immunogenic tumor. Clinical responses are despite immunotherapeutic interventions limited and currently responders can't be identified in advance.

This project will focus on the detection of myeloid suppressor cells (MSC) and regulatory T-cells (Tregs) in melanoma patients. Likewise the tumoral expression of immunomodulating proteins will be determined.