Code
3F000107
Duration
01 October 2007 → 30 September 2010
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Orthopaedics
- Orthopaedics
- Orthopaedics
Keywords
systemic lupus eryrthematosus and systemic slcerosis
anti-nuclear antibodies
connective tissue disease
lymphotoxin
central tolerance
Project description
The project starts from the observation that lymphotoxin deficiënt mice develop specific antinuclear antibodies. The aim of the project is to investigate when in the development of mice the absence of lymphotoxin is necessary of the induction of these antibodies, and to verify whether pathological aberrances of connective tissue diseases are present.