Project

Role of purinergic signaling in the pathophysiology of human chronic upper airway inflammation

Duration
01 January 2010 → 31 December 2015
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Otorhinolaryngology
    • Otorhinolaryngology
    • Speech, language and hearing sciences
    • Otorhinolaryngology
Keywords
p2-receptors nasal polyps adenosine triphosphate (ATP) chronic rhinosinusitis
 
Project description

Chronic rhinosinusitis are chronic airways diseases that display a high comorbidity with asthma. Evidence has accumulated showing that nucleotides such as adenosine triphosphate can regulate the function of immune cells and modulate inflammatory responses. With this project we aim to contribute to the identofication of the purenergic signaling pathways taht are implicated in the pathology of human upper airway conditions.