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Project

Deregulated mRNA transcription and protein translation in the transformation of normal T-cells to malignant cells.

Information

Project Team

Outputs and Outcomes

Publications

A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia

Lisa DemoenFilip MatthijssensLindy ReunesBruno PalhaisBéatrice LintermansSara T'SasIgor FijalkowskiJoachim TaminauMuluembet Z. AkeleSiska Van BelleTom TaghonDieter DeforceFilip Van NieuwerburghGeert BerxPanagiotis NtziachristosZeger DebyserKaat DurinckTim PietersSteven GoossensPieter Van Vlierberghe et al.

A1 Journal Article in SCIENCE ADVANCES

2024

A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia

Igor FijalkowskiJin WangQi JinJolien Van LaereValentina SerafinJohn D. CrispinoPanagiotis Ntziachristos

A1 Journal Article in LEUKEMIA

2024

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma

Stien De ConinckRenate De SmedtBéatrice LintermansLindy ReunesHansen J. KosasihAlexandra ReekmansLauren M. BrownNadine Van RoyBruno PalhaisJuliette RoelsMalaïka Van der LindenJo Van DorpePanagiotis NtziachristosFrederik W. Van DelftMarc R. MansourTim PietersTim LammensBarbara De MoerlooseCharles E. De BockSteven GoossensPieter Van Vlierberghe et al.

A1 Journal Article in HAEMATOLOGICA

2024