Project

Distribution and transport of uremic retention solutes: from modelling towards optimisation of hemodialysis

Duration
01 January 2014 → 31 December 2019
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Urology and nephrology
    • Urology and nephrology
    • Urology and nephrology
Keywords
uremic toxins protein-bound hemodialysis dialysis adequacy kinetics solute distribution
 
Project description

Kinetic models for different retention solutes like the protein-bound solutes are calibrated and validated based on in vitro and in vivo data. These models are further used to develop a new parameter to indicate hemodialysis adequacy as well as to optimise and personalise the hemodialysis treatment.