Project

The diagnostic and therapeutic potential of the tumor associated antigene xvB5 in non-small cell lung cancer

Duration
01 January 2007 → 31 October 2011
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Medicinal products
  • Engineering and technology
    • Biomaterials engineering
    • Biological system engineering
    • Biomaterials engineering
    • Biomechanical engineering
    • Other (bio)medical engineering
    • Environmental engineering and biotechnology
    • Industrial biotechnology
    • Other biotechnology, bio-engineering and biosystem engineering
Keywords
biomolecular engineering radio-immunotherapy xvB5
 
Project description

The purpose of the proposal encloses the development of recombinant, humanised anti-xvB5 antibody fragments adapated for radio-immunotherapy and radio-diagnosis in the treatment of non-small cell lung cancer. The biotechnological engineering, the labelling with radio-isotopes and the in vitro and in vivo evaluation in an experimental animal model will be investigated in the research project.