Code
01P08511
Duration
01 October 2011 → 01 October 2012
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Endocrinology and metabolic diseases
- Gynaecology and obstetrics
- Endocrinology and metabolic diseases
- Gynaecology and obstetrics
- Nursing
- Endocrinology and metabolic diseases
- Gynaecology and obstetrics
Keywords
embryonic stem cells
pluripotency
differentiation
blastocyst
Project description
Human uterine and blastocyst fluids will be analyzed to identify extrinsic (environment) and intrinsic (cell-cell contacts) factors that drive the inner cell mass of a blastocyst towards pluripotency or towards differentiation. Additionally, a comparable approach will be used to test the in vitro environment of embryonic stem cells for putative factors involved in maintenance of pluripotency.