Project

Identification and functional analysis of signaling molecules with a possible function in pluripotency and differentiation of embryonic stem cells

Code
01P08511
Duration
01 October 2011 → 01 October 2012
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Nursing
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
Keywords
embryonic stem cells pluripotency differentiation blastocyst
 
Project description

Human uterine and blastocyst fluids will be analyzed to identify extrinsic (environment) and intrinsic (cell-cell contacts) factors that drive the inner cell mass of a blastocyst towards pluripotency or towards differentiation. Additionally, a comparable approach will be used to test the in vitro environment of embryonic stem cells for putative factors involved in maintenance of pluripotency.