Research Explorer

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Project

MEFuran

Outputs and Outcomes

Publications

Synthesis and optimization of stapled DOCK peptides with improved drug-like properties

Atiruj TheppawongEwout De GeyterAnnemieke Madder

A1 Journal Article in ARKIVOC

Proximity-induced ligation and one-pot macrocyclization of 1,4-diketone-tagged peptides derived from 2,5-disubstituted furans upon release from the solid support

Alex ManicardiAtiruj TheppawongMarleen Van TroysAnnemieke Madder

A1 Journal Article in ORGANIC LETTERS

Photo-induced crosslinking uncovers an antiparallel strand orientation in heterodimeric (EIAALEK)(3)/(KIAALKE)(3) and (EIAALEK)(3)/(RIAALRE)(3) coiled-coil systems

Dorien AerssensLaia Miret CasalsD. GomezD. Sousa-NevesY. LevyM. De VleesschouwerAlex ManicardiAnnemieke Madder

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

A red light-triggered chemical tool for sequence-specific alkylation of G-quadruplex and I-motif DNA

Enrico CadoniLessandro De PaepeGertjan ColpaertRuben TackDries WaegemanAlex ManicardiAnnemieke Madder

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Synthesis and structure-activity relationship of peptide nucleic acid probes with improved interstrand-crosslinking abilities: application to biotin-mediated RNA-pulldown

Enrico CadoniFrancesca PennatiPenthip MuangkaewJoke ElskensAnnemieke MadderAlex Manicardi

A2 Journal Article in RSC CHEMICAL BIOLOGY

Hydrolysis of 5-methylfuran-2-yl to 2,5-dioxopentanyl allows for stable bio-orthogonal proximity-induced ligation

Alex ManicardiEnrico CadoniAnnemieke Madder

A1 Journal Article in COMMUNICATIONS CHEMISTRY