Code
3E011812
Duration
01 October 2012 → 30 September 2018
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Research disciplines
-
Natural sciences
- Regulation of metabolism
- Plant biochemistry
- Plant cell and molecular biology
Keywords
Medicago truncatula
triterpene saponins
homeostasis
ERAD
E3 ligases
Project description
The involvement of ERAD in triterpene homeostasis will be examined in Medicago truncatula. Proteins steering ERAD will be identified by several complementary approaches, including interactomic and transcriptomic analysis of plants misexpressing ERAD or saponin synthesis genes. Next, reverse genetics will be applied to examine the involvement of the candidate proteins in ERAD, triterpene homeostasis, and plant metabolism and physiology.