Project

Interaction of alphaherpesvirus glycoproteins with natural killer cells and dendritic cells

Duration
01 January 2011 → 31 December 2013
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Immunology
    • Laboratory medicine
    • Microbiology
Keywords
receptors glycoproteins NK cells alphaherpesvirus
 
Project description

Natural killer (NK) and dendritic cells (DC) are crucial in the antiviral immune response against alpaherpesviruses. The aims of the current research are to identify which viral glycoproteins are recognized by NK and/or DC, to analyze the consequences of this interaction on NK/DC activity, and to determine which receptors on NK/DC are responsible for this interaction.