Project

Peripheral back muscle dysfunctions and central pain mechanisms: An innovative perspective on differences between recurrent and chronic pain

Duration
01 January 2012 → 15 October 2017
Funding
Ghent University funding
Research disciplines
  • Social sciences
    • Biological and physiological psychology
    • Cognitive science and intelligent systems
    • Developmental psychology and ageing
  • Medical and health sciences
    • Neurosciences
    • Orthopaedics
    • Surgery
    • Neurosciences
    • Orthopaedics
    • Surgery
    • Nursing
    • Neurosciences
    • Orthopaedics
    • Surgery
Keywords
back muscles muscle dysfunction chronic pain central sensitization
 
Project description

In a case-control design, healthy volunteers are compared with patients with recurrent low back pain (during and after a pain flare), chronic low back pain, and fibromyalgia regarding peripheral muscle dysfunctions (CSA, fatty infiltration, fiber composition and muscle recruitment) and central mechanisms (temporal summation, pain inhibition, O&NS induced peripheral and central sensitization and cognitive emotional sensitization). This allows us to study interactions between peripheral and central mechanisms and their role in chroncity.