Code
01J01215
Duration
01 September 2015 → 30 June 2020
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Natural sciences
- Animal biology
- Microbiology
- Systems biology
-
Medical and health sciences
- Laboratory medicine
- Microbiology
- Laboratory medicine
- Laboratory medicine
- Microbiology
-
Agricultural and food sciences
- Agricultural animal production
- Veterinary medicine
- Other veterinary sciences
- Other agricultural and food sciences
Keywords
clostridium perfringens
vaccine
necrotic enteritis
Project description
The project aims to determine the surfactome and exoproteome of Clostridium perfringens in vitro after contact with chicken gut epithelial cells and at necrotic lesions in the gut of broiler chickens. Genes encoding proteins that are highly expressed under these conditions will be mutated and their role in the pathogenesis evaluated in in vivo.