Research Explorer

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Project

Transcriptional regulation of differentiation of human natural killer and innate lymphoid cells.

Outputs and Outcomes

Publications

IRF2 is required for development and functional maturation of human NK cells

Eva PersynSigrid WahlenLaura KiekensWouter Van LoockeHannah SiweEls Van AmmelZenzi De VosFilip Van NieuwerburghPatrick MatthysTom TaghonBart VandekerckhovePieter Van VlierbergheGeorges Leclercq et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells

Laura KiekensSigrid WahlenEva PersynZenzi De VosTom TaghonBart VandekerckhoveGeorges Leclercq

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

Sigrid WahlenFilip MatthijssensWouter Van LoockeSylvie TaveirneLaura KiekensEva PersynEls Van AmmelZenzi De VosStijn De MunterPatrick MatthysFilip Van NieuwerburghTom TaghonBart VandekerckhovePieter Van VlierbergheGeorges Leclercq et al.

A1 Journal Article in ELIFE

TXNIP promotes human NK cell development but is dispensable for NK cell functionality

Eva PersynSigrid WahlenLaura KiekensSylvie TaveirneWouter Van LoockeEls Van AmmelFilip Van NieuwerburghTom TaghonBart VandekerckhovePieter Van VlierbergheGeorges Leclercq et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES