Project

Functional profiling and therapeutic tolerization of macrophages in type 1 diabetes

Acronym
Macrophages in T1D
Code
41MC2312
Duration
01 March 2012 → 31 August 2012
Funding
European funding: framework programme
Research disciplines
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Endocrinology and metabolic diseases
    • Endocrinology and metabolic diseases
Keywords
type 1 diabetes
 
Project description

The research outlined in this application is designed to determine the functional phenotype of islet-infiltrating macrophages around diagnosis, their role in antigen shuttling to the pancreatic lymph nodes and their capacity to adopt a tolerogenic role upon treatment.