Project

Targeting the degradation of proteins involved in neuroblastoma and autoinflammatory diseases with bivalent ligands.

Code
01D27719
Duration
01 October 2019 → 31 October 2020
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Medicinal chemistry
Keywords
target degradation neuroblastoma auto-inflammation
 
Project description

In this project we aim to synthesize new bivalent ligands and evaluate/optimize these to tune the posttranslational degradation of protein targets involved in neuroblastoma and autoinflammatory diseases.