Acronym
SECRiFY-1
Code
01D07319
Duration
01 October 2019 → 01 November 2019
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Natural sciences
- Nucleic acids
- Proteins
- Posttranslational modifications
Keywords
Protein expression
secretory system
post-translational modifications
yeast
protein domains
proteomics
Project description
Recombinant protein production is a cornerstone of molecular life science, and a key enabling technology for biotechnological applications. Eukaryotic protein secretion is preferred. In this project, we will generate experimental secretability data on hundreds of thousands of protein (domain)fragments in yeast. This methodology allows us to investigate the influence of the
secretory signal and the chaperones on productive folding.