Project

Role and regulation of the anti-inflammatory protein A20 in selective autophagy

Code
3G027413
Duration
01 January 2013 → 31 December 2018
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Molecular and cell biology not elsewhere classified
  • Medical and health sciences
    • Dermatology
    • Gastro-enterology
    • Innate immunity
  • Engineering and technology
    • Biological control
    • Other biotechnology, bio-engineering and biosystem engineering not elsewhere classified
Keywords
signal transduction autophagy inflammation
 
Project description

Selective autophagy plays an important role in innate immunity and inflammation. Using several cellular models we will investigate if and how the anti-inflammatory protein A20 regulates autophagy. In addition, we will study the possible role of autophagy in the anti-inflammatory effects of A20.