Design space estimation and validation of an innovative continuous pharmaceutical production process

01 January 2012 → 31 December 2012
Regional and community funding: Special Research Fund
Research disciplines
  • Engineering and technology
    • Chemical product design and formulation
    • Biomaterials engineering
continuous processing design space validation Quality-by-Design (QbD)
Project description

The project focusses on the optimization and validation of a continuous granulation process. Based on the critical process parameters, the aim is to translate data collected from process analyzers into a space of process parameters, displayiing the probability to meet the product targeted performance. This allows predicting the process parameters leading to the expected product specifications with a high probability.