Project

Exercise and the 'human carnosinase paradox'

Duration
01 October 2012 → 30 September 2016
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Research disciplines
  • Social sciences
    • Education curriculum
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Physiology
    • Endocrinology and metabolic diseases
    • Physiology
    • Endocrinology and metabolic diseases
    • Physiology
Keywords
physical activity training oxidative stress
 
Project description

Genetic evidence was presented linking high carnosinase enzyme activity with some diseases. Serum carnosinase is the enzyme responsible for hydrolylis of carnosine, a bioactive dipeptide with antioxidant and antiglycative properties. In contrast to other animals, humans have a high carnosinase activity, called the human carnosinase paradox. This project aims to explore the relationship of the carnosinase paradox with exercise.