Code
3F019316
Duration
01 October 2016 → 25 May 2017
Funding
Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Social sciences
- Biological and physiological psychology
- Cognitive science and intelligent systems
- Developmental psychology and ageing
-
Medical and health sciences
- Gastro-enterology and hepatology
- Immunology
- Neurosciences
- Gastro-enterology and hepatology
- Immunology
- Neurosciences
- Gastro-enterology and hepatology
- Immunology
- Neurosciences
Keywords
gut-brain axis
TRAF6
Multiple Sclerosis
Project description
IL-17A-producing T helper (Th17) cells, which contribute to Multiple Sclerosis (MS), are educated by an immunological gut-brain axis, in which we suspect a role for intestinal epithelial TRAF6 signalling. Therefore, we will investigate the role of intestinal TRAF6 signalling in a mouse model of MS. Understanding such gut-derived immune effects on the brain might aid in designing novel MS therapies.