Research Explorer

Project

Hijacking of antigen-presenting cells by viruses to facilitate spread and subvert the immune response
Acronym
01GB1311
Code
01G01311
Duration
01 January 2011 → 31 October 2016
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Immunology
    • Laboratory medicine
    • Microbiology
Keywords
virus antigen-presenting cell dendritic cell
 
Project description
 

The research described in the proposal aims at determining how viruses are able to manipulate mucosal antigen-presenting cells (m-APC), with special emphasis on dendritic cells, to promote virus spread and/or disturb the antiviral immune response. Elucidating of the underlying mechanisms will allow the design of novel and more specific antiviral strategies.