Research Explorer

Project

Combining optogenetics, chemogenetics, intracranial electroencephalography and functional magnetic resonance imaging to investigate abnormal functioning of brain networks during epileptogenesis
Code
01IO1816
Duration
01 October 2016 → 30 September 2022
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Medical and health sciences
    • Neurophysiology
    • Neurophysiology
    • Neurophysiology
  • Engineering and technology
    • Biomedical image processing
    • Biomedical instrumentation
    • Biomedical modelling
    • Biomedical signal processing
Keywords
epileptogenesis
 
Project description
 

This project will investigate

  1. how brain networks change during the development of epilepsy using functional MRI, specific neuromodulation tools and advanced network analysis;
  2. whether epilepsy-related network changes are linked with the severity of epilepsy and the obtained efficacy of epilepsy therapies and
  3. whether these network changes can be reversed in order to suppress epileptic seizures.