Research Explorer

Project

Red-infrared quantum dots for application in blood point-of-care testing
Code
01D08017
Duration
01 November 2017 → 30 June 2020
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Analytical chemistry
    • Inorganic chemistry
    • Organic chemistry
    • Theoretical and computational chemistry
    • Other chemical sciences
  • Medical and health sciences
    • Diagnostics
    • Laboratory medicine
    • Diagnostics
    • Laboratory medicine
    • Medicinal products
    • Pharmaceutical analysis and quality assurance
    • Diagnostics
    • Laboratory medicine
Keywords
whole blood point-of care diagnostics alpha-fetoprotein des-gamma carboxyprothrombin redinfrared quantum dots nanoparticle-based immunoassay “sample preparation free” techniques
 
Project description
 

The goal of the project is to develop alpha-fetoprotein immunoassays in whole blood for effective point-of-care (POC) diagnostics, including optimal red-infrared (RIR) quantum dots (QDs), their surface modification, assay format and readout system. Comparison of assay outcomes for whole blood, plasma and serum will be performed to prove (or disprove) possibility of whole blood POC diagnostic based on immunoassay with RIR QD as label.