Research Explorer

Project

Swine as an intermediate host for potentially pandemic avian influenza viruses: unravelling host species barriers
Code
01D02017
Duration
01 January 2018 → 31 December 2021
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Public health care
    • Public health sciences
    • Public health services
    • Immunology
    • Laboratory medicine
    • Microbiology
Keywords
swine influenza pandemic H9N2 adaptation reassortment transmission
 
Project description
 

We will perform experimental pig infection studies to determine the genetic changes required for adaptation of an avian H9N2 influenza virus to pigs. We will also examine the host factors that contribute to the pathogenesis and transmissibility of avian influenza viruses in pigs and in ferrets (as a model for humans).