Research Explorer

Project

Recognition of alfaherpesvirus envelope glycoproteins by dendritic cells and natural killer cells
Code
01J29110
Duration
01 May 2010 → 28 February 2015
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Immunology
    • Laboratory medicine
    • Microbiology
Keywords
DC NK herpesvirus glycoproteins
 
Project description
 

Dendritic cells and natural killer cells are crucial for an efficient immune response against alphaherpesviruses. These cells are able, via an unknown mechanism, to recognize alphaherpesvirus envelope glycoproteins. The aim of the project proposal is to unravel this mechanism, which will lead to new virological and immunological insights that may lead to new strategies to interfere with alphaherpesvirus infections.