Research Explorer

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Project

Combining transcriptomics, epigenetics and in vivo CRISPR screens to unravel the cell-cell communication within the steady-state liver module (deLiver-CRISPR)

Outputs & Impact

Publications & research data ( 4 )

Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

Yong ChenEmily De LombaerdeAimee-Rose Bugler-LambZifu ZhongMartijn SchuijsClaudia Mariela Brenis GómezJamie De BaereMark GontsarikHeleen LauwersKim Deswarte et al.

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells

Mohamed Amer MusratiBenoit StijlemansAbdulkader AzouzDaliya KanchevaSarah MesbahiEva HadadiEls LebeggeLeen AliKaren De VlaminckIsabelle Scheyltjens et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

In vivo macrophage engineering as novel therapeutic strategy against liver metastasis

Marie LavironMartin Guilliams

Editorial material

Liver macrophages in health and disease

Martin GuilliamsCharlotte Scott

A1 Journal Article in IMMUNITY

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )