Research Explorer

Project

Generation, validation and application of nanobodies directed against the neovascular integrins alpha V and Beta 3 in cancer therapie
Code
365B2307
Duration
01 January 2007 → 31 December 2010
Funding
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Medical and health sciences
    • Immunology
    • Morphological sciences
    • Oncology
    • Immunology
    • Morphological sciences
    • Oncology
    • Immunology
    • Morphological sciences
    • Oncology
Keywords
therapy antibodies cancer
 
Project description

Research in this project is based on the finding that the integrins alphaV and Beta3 are expressed by cancerous endothelium and wound tissue specifically. The aim of the project is to destroy tumors by small antibodies that block these integrins.