Zebrafish transgenic and patient xenograft transplantation models of pediatric tumors for the pre-clinical drug testing

01 January 2015 → 31 December 2017
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Medical and health sciences
    • Pediatrics and neonatology
    • Pediatrics and neonatology
    • Nursing
    • Pediatrics and neonatology
pediatric tumors
Project description

Despite the success of the treatment and the relapse a major challenge in the last tackling childhood cancers decades been recognized is the toxicity (toxicity). For studies of new drugs less toxic to accelerate the process, the team uses Professor Speleman a recent experimental model, namely zebrafish. Previous studies showed that these fish are easily usable animals for testing new drugs. Moreover, they breed faster than mice, which saves time and money in the implementation of such experiments.