Project

High- and very-high-index metasurfaces for enhanced vibrational circular dichroism

Code
G0ACC26N
Duration
01 January 2026 → 31 December 2029
Funding
Research Foundation - Flanders (FWO)
Promotor-spokesperson
Research disciplines
  • Natural sciences
    • Optical physics not elsewhere classified
    • Spectroscopic methods
  • Engineering and technology
    • Nanophotonics
    • Sensors, biosensors and smart sensors not elsewhere classified
    • Metamaterials
Keywords
Circular dichroism Metasurfaces Chiral molecular sensing
 
Project description
Like our hands, molecules can come in right- and left-handed configurations. As most biomolecules like proteins or sugars appear in our bodies only in one of these possible configurations, determining molecular handedness is key in biochemistry and the pharmaceutical industry. Circular dichroism is a technique that uses polarized light to this end. Vibrational circular dichroism is a version of this method that looks at molecular vibrations using infrared light to fingerprint their chemical composition and conformation. However, current limitations in sensitivity at low concentrations or volumes hinder its application. This project will use nanostructures made of materials like silicon to amplify the interaction between chiral molecules and infrared light. By designing lattices of such resonators into so-called metasurfaces, researchers aim to boost the sensitivity of vibrational circular dichroism. This capability will enable a more accurate quantification of the purity of the handed chemicals used in medicines, perfumes, or food, with benefits for their effectiveness and safety.