The chemical industry is looking into advanced recycling techniques to manage large amounts of plastic waste discarded. A new emerging technology is supercritical hydrothermal liquefaction (SC-HTL), which is a thermochemical depolymerization process converting plastic waste with supercritical water into liquid energy carriers that can be used in aviation, ideally in so-called sustainable aviation fuel (SAF). Aviation is considered one of the hardest sectors to decarbonize but renewable fuels can reduce lifecycle emissions up to 80% compared to traditional fuels. SC-HTL of waste tires qualifies as potential SAF production route with the advantage that using proper conditions a fraction of the contaminants (heteroatomic species with O, N, S, Cl and Br) typically present in waste-derived oil is removed. In this project, new fundamental knowledge will be obtained about decomposition of waste tires under supercritical conditions using well-chosen model compounds. Experimental and kinetic modeling work based on first principles will be combined. To this end, the in-house automatic kinetic modeling framework will be expanded to supercritical conditions. Developed kinetic models will be validated with new experimental data and finally the calculation time of the model will be reduced using machine learning tools. Modeling of real waste tire decomposition will be enabled by extrapolation of kinetic insight from model compounds together with kinetic Monte Carlo simulations