Research Explorer

Project

Identification of bacteriocins with antibacterial activity against Clostridium difficile
Code
178DI0311
Duration
01 October 2010 → 05 January 2016
Funding
Regional and community funding: IWT/VLAIO
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Medical biochemistry and metabolism
    • Microbiology
    • Laboratory medicine
    • Medical biochemistry and metabolism
    • Laboratory medicine
    • Medical biochemistry and metabolism
    • Microbiology
Keywords
bacteriocins alternative antibiotic therapy clostridium difficile
 
Project description
 

Clostridium difficile is an anaerobic, sporulating, facultative pathogenic bacterium for humans as well as animals. The current antibiotic treatments appear to be less and less efficient. It is very important to look for possible alternative treatment methods. In this project, proteins (bacteriocins) will be identified that are able to inhibit Clostridium difficile but affect the normal microflora in a minimal way.