Aim of the CAFFEIN network is to provide 10 early stage researchers (ESRs) and 2 experienced researchers (ERs) with excellent training in an industry relevant area of cancer research, complementary skills required for pharmaceutical industry, and knowledge in setting up biomedical start-up companies. To this end, the network comprises a full industrial partners, the established pharmaceutical company medimmune, a global leader in immunopharmaceuticals, which trains two ERs. The research focus of CAFFEIN, which stands for Cancer Associated Fibroblasts(CAF) Function in Tumor Expansion and Invasion, is to understand the mechanisms, how fibroblastoid cells support tumor progression and metastasis formation, CAF biology is therefore rather complex, but the research groups of the CAFFEIN network cover many different aspects of it, thus having a critical mass to provide relevant training in this area