Project

Development of a therapeutic vaccine against Bovine Papillomavirus induced equine sarcoids

Code
01P00308
Duration
01 October 2008 → 30 September 2011
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Natural sciences
    • Other biological sciences
    • Other natural sciences
Keywords
vaccine Immune response VRP equine sarcoid
 
Project description

Selected and point mutated BPV genes will be subcloned into the Venezuelan Equine Encephalitis Virus Replicon Particles (VRP). Five horse will be immunized with these VRP’s and cellular immune response will be determined. The prophylactic effect of the vaccine will be determined after inoculation of these immunized animals with BPV-1 plasmid DNA. The therapeutic effect will be evaluated on 5 horses with naturally occurring equine sarcoids.