Code
179P4508
Looptijd
01-12-2007 → 01-12-2010
Financiering
Private funding via IWT/VLAIO
Promotor
Onderzoeksdisciplines
-
Social sciences
- Biological and physiological psychology
- Cognitive science and intelligent systems
- Developmental psychology and ageing
-
Medical and health sciences
- Gastro-enterology and hepatology
- Neurosciences
- Gastro-enterology and hepatology
- Neurosciences
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
- Gastro-enterology and hepatology
- Neurosciences
Trefwoorden
hersenen
hart
5-HT4 receptor
darm
Projectomschrijving
The influence of selective 5-HT4 receptor agonists on acetylcholine release from brain slices is examined for possible application in degenerative brain diseases, characterized by memory loss. Parallelly, the influence of the agonists is investigated on peripheral 5-HT4 receptors in the gastro-intestinal tract and in the heart to select the substances with as little peripheral effect as possible.